Saturday, October 6, 2012

Tryptophan


TRIP-toe-fan


Commonly used brand name(s)

In the U.S.


  • Aminomine

Available Dosage Forms:


  • Capsule

  • Tablet

Therapeutic Class: Nutriceutical


Uses For tryptophan


L-tryptophan is used along with other medications to treat mental depression. Also, L-tryptophan is used along with lithium to treat bipolar disorder.


Before Using tryptophan


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tryptophan, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to tryptophan or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Studies on tryptophan have been done only in adult patients, and there is no specific information comparing use of L-tryptophan in children with use in other age groups.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of L-tryptophan in the elderly with use in other age groups.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking tryptophan, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using tryptophan with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Isocarboxazid

  • Phenelzine

  • Tranylcypromine

Using tryptophan with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Clorgyline

  • Desvenlafaxine

  • Duloxetine

  • Fluoxetine

  • Milnacipran

  • Paroxetine

  • Selegiline

  • Sertraline

  • Sibutramine

  • Vilazodone

Using tryptophan with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Fluvoxamine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of tryptophan. Make sure you tell your doctor if you have any other medical problems, especially:


  • Achlohydria or malabsorption (digestion problems)—L-tryptophan may cause breathing problems in patients with certain types of digestion problems

  • Bladder cancer—L-tryptophan may increase the risk of bladder cancer

  • Cataracts—L-tryptophan may cause cataracts

  • Diabetes mellitus (sugar diabetes)—L-tryptophan may cause diabetes in patients with a family history of diabetes

Proper Use of tryptophan


Take with a low-protein, carbohydrate-rich meal or snack to prevent an upset stomach.


Dosing


The dose of tryptophan will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of tryptophan. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage forms (capsules or tablets):
    • For mental depression:
      • Adults—8 to 12 grams per day, given in 3 to 4 equally divided doses

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of tryptophan, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using tryptophan


It is important that your doctor check your progress at regular visits, to allow dosage adjustments and help reduce any side effects.


tryptophan may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to tryptophan before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.


tryptophan may cause dryness of the mouth. Using sugarless candy or gum, ice, or a saliva substitute may be helpful. Check with your physician or dentist if dry mouth continues for more than 2 weeks.


Avoid excessive exposure to ultraviolet light to reduce the chance of cataract formation.


tryptophan Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Symptoms of overdose

Get emergency help immediately if any of the following symptoms of overdose occur:


  • Agitation

  • confusion

  • diarrhea

  • fever

  • overactive reflexes

  • poor coordination

  • restlessness

  • shivering

  • sweating

  • talking or acting with excitement you cannot control

  • trembling or shaking

  • twitching

  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Dizziness

  • drowsiness

  • dry mouth

  • headache

  • loss of appetite

  • nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More tryptophan resources


  • Tryptophan Drug Interactions
  • Tryptophan Support Group
  • 3 Reviews for Tryptophan - Add your own review/rating


Compare tryptophan with other medications


  • ADHD
  • Anxiety
  • Depression
  • Insomnia
  • Premenstrual Dysphoric Disorder
  • Smoking Cessation


Stromectol


Generic Name: ivermectin (Oral route)

eye-ver-MEK-tin

Commonly used brand name(s)

In the U.S.


  • Stromectol

Available Dosage Forms:


  • Tablet

Therapeutic Class: Anthelmintic


Chemical Class: Avermectin


Uses For Stromectol


Ivermectin is used in the treatment of certain worm infections. It is used to treat river blindness (onchocerciasis) and a certain type of diarrhea (strongyloidiasis). It may also be used for some other kinds of worm infections.


Ivermectin appears to work by paralyzing and then killing the offspring of adult worms. It may also slow down the rate at which adult worms reproduce. This results in fewer worms in the skin, blood, and eyes.


Ivermectin is available only with your doctor's prescription.


Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, ivermectin is used in certain patients with the following medical condition:


  • Bancroft's filariasis

  • Scabies

Before Using Stromectol


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Studies on this medicine have been done only in adults and in children weighing 15 kilograms (kg) (33 pounds) and over, and there is no specific information comparing use of ivermectin in children weighing less than 15 kg with use in other age groups.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ivermectin in the elderly with use in other age groups.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Bronchial asthma—Ivermectin may make this problem worse.

Proper Use of Stromectol


Ivermectin is best taken as a single dose with a full glass (8 ounces) of water on an empty stomach (1 hour before breakfast), unless otherwise directed by your doctor.


To help clear up your infection, take this medicine exactly as directed. Your doctor may want you to take another dose every 3 to 12 months.


Your doctor may also prescribe a corticosteroid (a cortisone-like medicine) for certain patients with river blindness, especially those with severe symptoms. This is to help reduce the inflammation caused by the death of the worms. If your doctor prescribes these two medicines together, it is important to take the corticosteroid along with ivermectin. Take them exactly as directed by your doctor. Do not miss any doses.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For river blindness:
      • Adults and teenagers—Dose is based on body weight and must be determined by your doctor. The usual dose is 150 micrograms (mcg) per kilogram (kg) (68 mcg per pound) of body weight as a single dose. The treatment may be repeated every three to twelve months.

      • Children—Dose is based on body weight and must be determined by your doctor. For children weighing 15 kg (33 pounds) or more, the usual dose is 150 mcg per kg (68 mcg per pound) of body weight as a single dose. If necessary, the treatment may be repeated every three to twelve months. For children weighing less than 15 kg, use and dose must be determined by your doctor.


    • For strongyloidiasis:
      • Adults and teenagers—Dose is based on body weight and must be determined by your doctor. The usual dose is 200 micrograms (mcg) per kilogram (kg) (91 mcg per pound) of body weight as a single dose. Additional doses usually are not needed.

      • Children—Dose is based on body weight and must be determined by your doctor. For children weighing 15 kg (33 pounds) or more, the usual dose is 200 mcg per kg (91 mcg per pound) of body weight as a single dose. For children weighing less than 15 kg, use and dose must be determined by your doctor.



Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Stromectol


It is important that your doctor check your progress at regular visits. This is to help make sure that the infection is cleared up completely. In addition, if you have river blindness (onchocerciasis), your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). If you have a certain type of diarrhea (strongyloidiasis), your doctor may want to examine three stool samples. This should be done over the 3-month period following treatment.


If your symptoms become worse, check with your doctor.


This medicine may cause some people to become lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are lightheaded. If these reactions occur, check with your doctor.


Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests (blood or liver tests) may be affected by this medicine.


Stromectol Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Less common—for the treatment of river blindness (onchocerciasis) only
  • Eye or eyelid irritation, pain, redness, or swelling

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common—for the treatment of river blindness (onchocerciasis) only
  • Fever, itching or skin rash

  • joint or muscle pain

  • painful and tender glands in neck, armpits, or groin

  • rapid heartbeat

Less common—for the treatment of river blindness (onchocerciasis) only
  • Headache

  • swelling of the face, hands, arms, feet, or legs

Less common—for the treatment of strongyloidiasis only
  • Diarrhea

  • dizziness

  • skin rash or itching

Rare—for the treatment of river blindness (onchocerciasis) only
  • Lightheadedness when getting up from a lying or sitting position

Rare—for the treatment of strongyloidiasis only
  • Loss of appetite

  • shaking or trembling

  • sleepiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Stromectol side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Stromectol resources


  • Stromectol Side Effects (in more detail)
  • Stromectol Dosage
  • Stromectol Use in Pregnancy & Breastfeeding
  • Drug Images
  • Stromectol Drug Interactions
  • Stromectol Support Group
  • 2 Reviews for Stromectol - Add your own review/rating


  • Stromectol Prescribing Information (FDA)

  • Stromectol MedFacts Consumer Leaflet (Wolters Kluwer)

  • Stromectol Concise Consumer Information (Cerner Multum)

  • Stromectol Monograph (AHFS DI)

  • Ivermectin Prescribing Information (FDA)



Compare Stromectol with other medications


  • Ascariasis
  • Cutaneous Larva Migrans
  • Filariasis, Elephantiasis
  • Head Lice
  • Onchocerciasis, River Blindness
  • Scabies
  • Strongyloidiasis


Friday, October 5, 2012

Solage Topical


Generic Name: mequinol and tretinoin (Topical route)


ME-kwin-ol, TRET-i-noin


Commonly used brand name(s)

In the U.S.


  • Solage

Available Dosage Forms:


  • Solution

Therapeutic Class: Hypopigmentation Agent


Chemical Class: Retinoid


Uses For Solage


Mequinol and Tretinoin is used to treat areas of the skin that have become darker after repeated exposure to the sun. These areas are called solar lentigines, or age or liver spots.


Mequinol and tretinoin is available only with your doctor's prescription.


Before Using Solage


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of this medicine in children with use in other age groups. Mequinol and tretinoin should not be used in children.


Geriatric


This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersXStudies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Aminocaproic Acid

  • Aprotinin

  • Tetracycline

  • Tranexamic Acid

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Fluconazole

  • Ketoconazole

  • Voriconazole

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Eczema or

  • Frequent exposure to sunlight or sunlamps or

  • Sunburn—Use of this medicine may cause or increase the irritation associated with these conditions

  • Vitiligo (or a family history of this condition)—Use of this medicine may cause lightening of areas of the skin that have not been treated

Proper Use of Solage


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.


Do not apply this medicine to windburned or sunburned skin or on open wounds.


Do not use this medicine in or around the eyes or lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidentally gets on these areas, wash with water at once.


This medicine usually comes with patient directions. Read them carefully before using the medicine.


To use this medicine:


  • Using the applicator tip, apply enough mequinol and tretinoin solution to cover the affected areas. Apply only enough medicine to make the lesion appear moist. Avoid areas of normally colored skin.

  • You should not shower or bathe for at least 6 hours after applying the medicine.

  • Cosmetics may be applied 30 minutes after application of the medicine.

Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For topical dosage form (solution):
    • For age or liver spots:
      • Adults —Apply to the affected areas of the skin twice daily, morning and evening, at least 8 hours apart.

      • Children—Use is not recommended.



Missed Dose


If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


The product is flammable and should be kept away from fire or excessive heat.


Precautions While Using Solage


You may notice redness, stinging, burning or irritation when you first start using this medicine. It may take up to 6 months before you notice full beneficial effects, even if you use the medicine every day. Check with your health care professional at any time skin irritation becomes severe or if your age spots get darker in color.


Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as mequinol and tretinoin topical solution:


  • Hair products that are irritating, such as permanents or hair removal products

  • Skin products that cause sensitivity to the sun, such as those containing spices or limes

  • Skin products containing a large amount of alcohol, such as astringents, shaving creams, or after-shave lotions

  • Skin products that are too drying or abrasive, such as some cosmetics, soaps, or skin cleansers

Using these products along with mequinol and tretinoin may cause mild to severe irritation of the skin. Check with your doctor before using other topical medicines.


Avoid overexposing the treated areas to sunlight, wind, or cold weather. The skin will be more prone to sunburn, dryness, or irritation. Do not use a sunlamp.


Regularly use sunscreen or sunblocking lotions with a sun protection factor (SPF) of at least 15. Also, wear protective clothing and hats, and apply creams, lotions, or moisturizers often.


Check with your doctor any time your skin becomes too dry and irritated. Your health care professional can help you choose the right skin products for you to reduce skin dryness and irritation and may include :


  • Taking part in an ongoing program to avoid further damage to your skin from the sun. The program should stress staying out of the sun when possible and wearing proper clothing or hats to protect your skin from sunlight.

  • Regular use of oil-based creams or lotions to help to reduce skin irritation or dryness caused by the use of mequinol and tretinoin topical solution.

Solage Side Effects


In some animal studies, mequinol and tretinoin has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other studies have not shown the same result and more studies need to be done. It is not known if mequinol and tretinoin topical solution causes skin tumors to develop faster in humans.


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


More common
  • Burning feeling or stinging skin (severe)

  • itching (severe)

  • peeling of skin (severe)

  • redness of skin (severe)

Less common
  • Allergic reaction

  • large blisters on the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Burning feeling, stinging, or tingling of skin (mild)—lasting for a short time after first applying the medicine

  • itching (mild)

  • chapping or slight peeling of skin (mild)

  • lightening of skin around treated area

  • lightening of skin on treated area

  • redness of skin (mild)

  • skin irritation

  • unusually warm skin (mild)

Less common
  • Crusting of skin

  • dry skin

  • skin rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Solage Topical side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Solage Topical resources


  • Solage Topical Side Effects (in more detail)
  • Solage Topical Use in Pregnancy & Breastfeeding
  • Solage Topical Drug Interactions
  • Solage Topical Support Group
  • 0 Reviews for Solage Topical - Add your own review/rating


Compare Solage Topical with other medications


  • Dermatological Disorders


Sunday, September 30, 2012

SSKI Drops


Pronunciation: poe-TASS-ee-uhm EYE-oh-dide
Generic Name: Potassium Iodide
Brand Name: SSKI


SSKI Drops are used for:

Treating lung conditions or disease in which mucus complicates the condition (eg, emphysema, bronchial asthma, bronchitis). It may also be used for other conditions as determined by your doctor.


SSKI Drops are an expectorant. It works by thinning mucous secretions (phlegm) in the lungs and making it less sticky. The mucus is easier to cough up. This reduces chest congestion, which helps make your coughs more productive.


Do NOT use SSKI Drops if:


  • you are allergic to any ingredient in SSKI Drops

  • you have iodine poisoning, Addison disease, kidney disease, lung disease, a skin disorder, stomach disorders, tuberculosis, or a history of preexisting thyroid disease

  • you are taking potassium sparing diuretics (eg, spironolactone) or potassium supplements

Contact your doctor or health care provider right away if any of these apply to you.



Before using SSKI Drops:


Some medical conditions may interact with SSKI Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have an overactive thyroid

Some MEDICINES MAY INTERACT with SSKI Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Lithium because side effects of SSKI Drops may be increased

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, captopril), aldosterone blockers (eg, eplerenone), or potassium sparing diuretics (eg, spironolactone) because serious side effects, including high blood potassium and irregular heartbeat, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if SSKI Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use SSKI Drops:


Use SSKI Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • SSKI Drops may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Dilute each dose in a glass (8 oz/240 mL) of water or fruit juice before taking.

  • Use the dropper that comes with SSKI Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of SSKI Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use SSKI Drops.



Important safety information:


  • Do not use a salt substitute or a potassium supplement without checking with your doctor.

  • Stop taking SSKI Drops and contact your health care provider if any of the following signs of iodine poisoning occur: burning of the mouth or throat; severe headache; metallic taste in mouth; soreness of the teeth and gums; irritation of the eyes with swelling of the eyelids; increased salivation.

  • Caution is advised when using SSKI Drops in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: SSKI Drops may cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using SSKI Drops during pregnancy. SSKI Drops are excreted in breast milk. Do not breast-feed while taking SSKI Drops.


Possible side effects of SSKI Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Acne; diarrhea; loss of appetite; nausea; upset stomach; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; confusion; fever; irregular heartbeat; metallic taste in the mouth; mouth sores; numbness or tingling of the hands or feet; skin rash; stomach pains; swelling in the neck or throat; unusual tiredness; weakness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: SSKI side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include burning of the mouth or throat; muscle weakness; severe headache; soreness of teeth or gums; swelling; irregular heartbeat.


Proper storage of SSKI Drops:

Store SSKI Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep SSKI Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about SSKI Drops, please talk with your doctor, pharmacist, or other health care provider.

  • SSKI Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about SSKI Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More SSKI resources


  • SSKI Side Effects (in more detail)
  • SSKI Use in Pregnancy & Breastfeeding
  • SSKI Drug Interactions
  • SSKI Support Group
  • 0 Reviews for SSKI - Add your own review/rating


Compare SSKI with other medications


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Saturday, September 29, 2012

Tapentadol


Pronunciation: ta-PEN-ta-dol
Generic Name: Tapentadol
Brand Name: Nucynta


Tapentadol is used for:

Treating moderate to severe acute pain in certain patients.


Tapentadol is a narcotic pain reliever. It works in certain areas of the brain and nervous system to decrease pain.


Do NOT use Tapentadol if:


  • you are allergic to any ingredient in Tapentadol

  • you have very slow, shallow, or difficult breathing; severe lung problems (eg, severe asthma, wheezing, shortness of breath); severe hypercapnia (high blood carbon dioxide levels); or you are having an asthma attack

  • you have or may have paralytic ileus (bowel paralysis)

  • you have severe kidney or liver problems

  • you are taking another medicine that contains tapentadol

  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Tapentadol:


Some medical conditions may interact with Tapentadol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of liver or kidney problems; stomach or bowel problems, blockage, or surgery; gallbladder problems; thyroid problems; metabolism problems; adrenal problems (eg, Addison disease); enlarged prostate; trouble urinating; curvature of the spine (scoliosis); or pancreas problems (eg, pancreatitis)

  • if you have or have recently had any head injury, brain injury or tumor, increased pressure in the brain, or infection of the brain or nervous system

  • if you have a history of lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD], sleep apnea), a heart problem called cor pulmonale, low blood pressure, or a seizure disorder (eg, epilepsy)

  • if you have severe drowsiness, constipation, hypercapnia, hypoxia (low blood oxygen levels), dehydration or low blood volume, poor health, or are severely overweight

  • if you have a history of mental or mood problems (eg, depression, anxiety, hallucinations), are going through withdrawal from alcohol or other substances, or if you or a family member have a history of alcohol or other substance abuse

Some MEDICINES MAY INTERACT with Tapentadol. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticholinergics (eg, scopolamine, oxybutynin) because they may increase the risk of constipation or difficulty urinating

  • MAOIs (eg, phenelzine), serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, paroxetine), St. John's wort, tricyclic antidepressants (eg, amitriptyline), or triptans (eg, sumatriptan) because a severe side effect called serotonin syndrome may occur. Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea

  • Other opioid pain medicines (eg, codeine, hydrocodone), muscle relaxers (eg, cyclobenzaprine), phenothiazines (eg, chlorpromazine), or medicines used for allergies, mental or mood disorders, nausea, or sleep disorders because the risk of side effects, including severe drowsiness, trouble breathing, or low blood pressure, may be increased

  • Buprenorphine, butorphanol, nalbuphine, naltrexone, or pentazocine because they may decrease Tapentadol's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tapentadol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Tapentadol:


Use Tapentadol as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Tapentadol comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Tapentadol refilled.

  • Take Tapentadol by mouth with or without food.

  • If you have been taking Tapentadol regularly, do not suddenly stop taking it. You may have an increased risk of withdrawal symptoms. If you need to stop Tapentadol, your doctor will gradually lower your dose.

  • If you miss a dose of Tapentadol and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tapentadol.



Important safety information:


  • Tapentadol may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Tapentadol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol while you are using Tapentadol.

  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tapentadol; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Tapentadol may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of this effect.

  • Do NOT take more than the recommended dose, change your dose, or use for longer than prescribed without checking with your doctor.

  • Tapentadol may cause constipation. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Talk to your doctor about using fiber laxatives or stool softeners to prevent or treat constipation while you use Tapentadol.

  • Tell your doctor or dentist that you take Tapentadol before you receive any medical or dental care, emergency care, or surgery.

  • Tapentadol may increase the risk of seizures in certain patients, including patients who have a history of seizures. Talk to your doctor to see if you may have a greater risk of seizures while taking Tapentadol. Seek immediate medical attention if you have a seizure.

  • Serotonin syndrome is a possibly fatal syndrome that can be caused by Tapentadol. Your risk may be greater if you take Tapentadol with certain other medicines (eg, "triptans," MAOIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.

  • Use Tapentadol with caution in the ELDERLY; they may be more sensitive to its effects, especially breathing problems, constipation, weakness or tiredness, and severe light-headedness.

  • Tapentadol should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Tapentadol may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tapentadol while you are pregnant. It is not known if Tapentadol is found in breast milk. Do not breast-feed while taking Tapentadol.

When used for long periods of time or at high doses, Tapentadol may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Tapentadol stops working well. Do not take more than prescribed.


Some people who use Tapentadol for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you suddenly stop taking Tapentadol, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.



Possible side effects of Tapentadol:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; dizziness; drowsiness; dry mouth; itching; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); agitation; burning, numbness, or tingling; chest pain; cold, clammy skin; confusion; difficult or increased urination; difficult, slow, or shallow breathing; disorientation; fainting; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; memory problems; mood or mental changes; seizures; severe or persistent dizziness, drowsiness, or light-headedness; trouble talking, thinking, or walking.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Tapentadol side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish skin; cold, clammy skin; difficult, slow, or shallow breathing; drowsiness leading to unresponsiveness or coma; excessive sweating; limp muscles; pinpoint pupils; seizures; slow or irregular heartbeat; vomiting.


Proper storage of Tapentadol:

Store Tapentadol between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tapentadol out of the reach of children and away from pets.


General information:


  • If you have any questions about Tapentadol, please talk with your doctor, pharmacist, or other health care provider.

  • Tapentadol is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tapentadol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tapentadol resources


  • Tapentadol Side Effects (in more detail)
  • Tapentadol Dosage
  • Tapentadol Use in Pregnancy & Breastfeeding
  • Tapentadol Drug Interactions
  • Tapentadol Support Group
  • 105 Reviews for Tapentadol - Add your own review/rating


  • Tapentadol Professional Patient Advice (Wolters Kluwer)

  • tapentadol Advanced Consumer (Micromedex) - Includes Dosage Information

  • Nucynta Prescribing Information (FDA)

  • Nucynta Monograph (AHFS DI)

  • Nucynta Consumer Overview

  • Nucynta ER Prescribing Information (FDA)



Compare Tapentadol with other medications


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Wednesday, September 26, 2012

Somatropin (rDNA origin - Refrigerated)


Pronunciation: SOE-ma-TROE-pin
Generic Name: Somatropin (rDNA origin - Refrigerated)
Brand Name: Nutropin AQ NuSpin


Somatropin (rDNA origin - Refrigerated) is used for:

Treating certain children or adults when the body does not produce enough growth hormone. It is also used to treat certain children who are not growing normally due to Turner syndrome or other conditions (eg, chronic kidney problems, idiopathic short stature). It may also be used for other conditions as determined by your doctor.


Somatropin (rDNA origin - Refrigerated) is a growth hormone that produces effects that are identical to the body's naturally occurring growth hormone. It affects the growth of bones, muscles, internal organs, and other tissues of the body.


Do NOT use Somatropin (rDNA origin - Refrigerated) if:


  • you are allergic to any ingredient in Somatropin (rDNA origin - Refrigerated)

  • you have been or are being treated for cancer or any unusual growths or tumors (especially in the brain) that may still be growing

  • you have premature epiphyseal closure (your bone growth is complete) or a serious illness caused by complications from surgery, trauma, or severe breathing problems (eg, respiratory failure)

  • you have certain eye problems caused by diabetes (eg, diabetic retinopathy)

  • you have Prader-Willi syndrome and are severely overweight or have severe breathing problems

Contact your doctor or health care provider right away if any of these apply to you.



Before using Somatropin (rDNA origin - Refrigerated):


Some medical conditions may interact with Somatropin (rDNA origin - Refrigerated). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have endocrine problems, including pituitary or adrenal gland problems; diabetes or a family history of diabetes; eye problems caused by diabetes; or an underactive thyroid

  • if you have a history of leukemia, unusual growths or tumors (especially in the brain), or cancer

  • if you have curvature of the spine (scoliosis), kidney or liver problems, ear or hearing problems (eg, repeated ear infection), Prader-Willi syndrome, are severely overweight, or have had recent major surgery or trauma

Some MEDICINES MAY INTERACT with Somatropin (rDNA origin - Refrigerated). Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Corticosteroids (eg, prednisone) because they may decrease Somatropin (rDNA origin - Refrigerated)'s effectiveness

  • Anticonvulsants (eg, phenytoin, carbamazepine) or cyclosporine because the risk of their side effects may be increased or their effectiveness may be decreased by Somatropin (rDNA origin - Refrigerated)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Somatropin (rDNA origin - Refrigerated) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Somatropin (rDNA origin - Refrigerated):


Use Somatropin (rDNA origin - Refrigerated) as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Somatropin (rDNA origin - Refrigerated). Talk to your pharmacist if you have questions about this information.

  • Somatropin (rDNA origin - Refrigerated) is given as an injection. A health care provider will teach you how to use it. Be sure you understand how to use Somatropin (rDNA origin - Refrigerated). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Allow Somatropin (rDNA origin - Refrigerated) to come to room temperature before you use it.

  • Check the injection device to be sure the correct dose is dialed before you use a dose of Somatropin (rDNA origin - Refrigerated).

  • Wash your hands before and immediately after using Somatropin (rDNA origin - Refrigerated).

  • Use a new needle each time you inject Somatropin (rDNA origin - Refrigerated). Do not reuse needles.

  • Do not use Somatropin (rDNA origin - Refrigerated) if it contains particles, is cloudy or discolored, or if the pen or cartridge is cracked or damaged.

  • Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle.

  • Always rotate injection sites each time you use Somatropin (rDNA origin - Refrigerated).

  • Do not shake Somatropin (rDNA origin - Refrigerated). Swirl gently to mix it.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Somatropin (rDNA origin - Refrigerated), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Somatropin (rDNA origin - Refrigerated).



Important safety information:


  • Somatropin (rDNA origin - Refrigerated) may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Somatropin (rDNA origin - Refrigerated) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Rare, sometimes fatal, lung and breathing problems may be caused by Somatropin (rDNA origin - Refrigerated) in CHILDREN with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or children with existing serious lung or breathing problems. Children should be checked for certain breathing problems before and during treatment. If your child develops a limp or complains of hip or knee pain during treatment with Somatropin (rDNA origin - Refrigerated), contact your doctor immediately. Tell your doctor immediately if your child becomes very sick or is hospitalized while using Somatropin (rDNA origin - Refrigerated). Somatropin (rDNA origin - Refrigerated) may need to be stopped.

  • Pancreas inflammation (pancreatitis) has been reported rarely in patients who take Somatropin (rDNA origin - Refrigerated). The risk may be greater in children, especially in girls who have Turner syndrome. Contact your doctor right away if you develop stomach or back pain.

  • Rarely, children using Somatropin (rDNA origin - Refrigerated) have experienced a slipped growth plate in the hip. Contact the doctor right away if the patient develops hip or knee pain or a limp.

  • Somatropin (rDNA origin - Refrigerated) may have benzyl alcohol, metacresol, or glycerin in it. Tell your doctor if you have ever had sensitivity or an allergic reaction to benzyl alcohol, metacresol, or glycerin.

  • Diabetes patients - Somatropin (rDNA origin - Refrigerated) may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine or your diet.

  • Lab tests, including blood sugar levels and thyroid function, may be performed while you use Somatropin (rDNA origin - Refrigerated). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Somatropin (rDNA origin - Refrigerated) with caution in the ELDERLY; they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Somatropin (rDNA origin - Refrigerated) while you are pregnant. It is not known if Somatropin (rDNA origin - Refrigerated) is found in breast milk. If you are or will be breast-feeding while you use Somatropin (rDNA origin - Refrigerated), check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Somatropin (rDNA origin - Refrigerated):


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Discomfort at the injection site; mild swelling (eg, of the hands or feet); muscle or joint pain.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); body pain or stiffness; burning, tingling, itching, or numbness in the palm of the hand, fingers, or wrist; change in appearance or size of a mole; chest pain; confusion; constant feeling of need to empty the bowel; curvature of the spine; depression; ear pain, discharge, or discomfort; excessive thirst or hunger; fast heartbeat; fever; frequent urination; hearing problems; increased pressure in the head or eye; infection; nausea; one-sided weakness; severe or persistent stomach or back pain; severe or persistent swelling of the ankles, legs, hands, or feet; slurred speech; sudden, severe, or persistent headache or dizziness; visual changes; vomiting.


Children: Ear discomfort or infection; fatigue or weakness; fever, persistent cough, or trouble breathing; hip or knee pain; leukemia; limp; seizures; snoring or irregular breathing during sleep; worsening of psoriasis.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Somatropin (rDNA origin - Refrigerated) side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include excessive thirst or hunger; frequent urination; headache; nausea or vomiting; swelling of the ankles, feet, or hands.


Proper storage of Somatropin (rDNA origin - Refrigerated):

Before mixing, store Somatropin (rDNA origin - Refrigerated) in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Protect from heat, moisture, and light. Do not use Somatropin (rDNA origin - Refrigerated) past the expiration date on the product label. After mixing, store Somatropin (rDNA origin - Refrigerated) according to the product label. Contact your pharmacist if you have any questions about the proper storage of Somatropin (rDNA origin - Refrigerated). Keep Somatropin (rDNA origin - Refrigerated), as well as needles and syringes, out of the reach of children and away from pets.


General information:


  • If you have any questions about Somatropin (rDNA origin - Refrigerated), please talk with your doctor, pharmacist, or other health care provider.

  • Somatropin (rDNA origin - Refrigerated) is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Somatropin (rDNA origin - Refrigerated). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Somatropin (rDNA origin - Refrigerated) resources


  • Somatropin (rDNA origin - Refrigerated) Side Effects (in more detail)
  • Somatropin (rDNA origin - Refrigerated) Use in Pregnancy & Breastfeeding
  • Somatropin (rDNA origin - Refrigerated) Drug Interactions
  • Somatropin (rDNA origin - Refrigerated) Support Group
  • 13 Reviews for Somatropin (rDNA origin - Refrigerated) - Add your own review/rating


Compare Somatropin (rDNA origin - Refrigerated) with other medications


  • Adult Human Growth Hormone Deficiency
  • AIDS Related Wasting
  • Burns, Nitrogen Retention
  • Cachexia
  • Growth Retardation, Chronic Renal Failure
  • Hypopituitarism
  • Idiopathic Short Stature
  • Noonan's Syndrome
  • Pediatric Growth Hormone Deficiency
  • Short Bowel Syndrome
  • Short Stature for Age
  • Turner's Syndrome


Tuesday, September 25, 2012

Nifedipine



Pronunciation: nye-FED-i-peen
Generic Name: Nifedipine
Brand Name: Procardia


Nifedipine is used for:

Treating certain kinds of angina (chest pain). It may also be used for other conditions as determined by your doctor.


Nifedipine is a calcium channel blocking agent. It works to decrease chest pain by dilating (widening) blood vessels in the heart and other blood vessels.


Do NOT use Nifedipine if:


  • you are allergic to any ingredient in Nifedipine

  • you have very low blood pressure or shock due to heart problems

  • you have had a heart attack within the past 2 weeks

  • you are taking a barbiturate (eg, phenobarbital), carbamazepine, a hydantoin (eg, phenytoin), a rifamycin (eg, rifampin, rifabutin), or St. John's wort

Contact your doctor or health care provider right away if any of these apply to you.



Before using Nifedipine:


Some medical conditions may interact with Nifedipine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of angina, heart blood vessel problems, or other heart problems (eg, aortic stenosis; congestive heart failure; heart attack; fast, slow, or irregular heartbeat); high or low blood pressure; liver problems (eg, cirrhosis); kidney problems; swelling of the arms or legs; or fluid in your lungs

  • if you take medicines to lower your blood pressure

  • if you have recently had or will be having surgery, or if you have recently stopped taking a beta-blocker (eg, propranolol)

Some MEDICINES MAY INTERACT with Nifedipine. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Alpha-blockers (eg, doxazosin), beta-blockers (eg, propranolol), diuretics (eg, hydrochlorothiazide, furosemide), methyldopa, or phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil, tadalafil) because the risk of low blood pressure may be increased

  • Acarbose because high blood sugar may occur

  • Azole antifungals (eg, ketoconazole, fluconazole), calcium channel blockers (eg, diltiazem, verapamil), cimetidine, fluoxetine, HIV protease inhibitors (eg, ritonavir, saquinavir), imatinib, macrolide antibiotics (eg, erythromycin, clarithromycin), nefazodone, streptogramins (eg, quinupristin/dalfopristin), or valproic acid because they may increase the risk of Nifedipine's side effects

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), rifamycins (eg, rifampin, rifabutin), or St. John's wort because they may decrease Nifedipine's effectiveness

  • Cyclosporine, digoxin, ketanserin, lithium, tacrolimus, theophylline, or vinca alkaloids (eg, vincristine) because the risk of their side effects may be increased by Nifedipine

  • Quinidine, theophylline, or vinca alkaloids (eg, vincristine) because their effectiveness may be decreased by Nifedipine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nifedipine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Nifedipine:


Use Nifedipine as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Nifedipine by mouth with or without food.

  • Do not eat grapefruit or drink grapefruit juice while you use Nifedipine.

  • Swallow Nifedipine whole. Do not break, crush, or chew before swallowing.

  • Do not suddenly stop taking Nifedipine without checking with your doctor. If you need to stop Nifedipine, your doctor may gradually lower your dose.

  • If you miss a dose of Nifedipine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nifedipine.



Important safety information:


  • Nifedipine may cause dizziness or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Nifedipine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Nifedipine may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, stit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • Proper dental care is important while you are taking Nifedipine. Brush and floss your teeth and visit the dentist regularly.

  • Tell your doctor or dentist that you take Nifedipine before you receive any medical or dental care, emergency care, or surgery.

  • If your doctor has instructed you to check your blood pressure regularly, be sure to do so.

  • Use Nifedipine with caution in the ELDERLY; they may be more sensitive to its effects.

  • Nifedipine should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nifedipine while you are pregnant. Nifedipine is found in breast milk. Do not breast-feed while taking Nifedipine.


Possible side effects of Nifedipine:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; cough; dizziness; flushing; giddiness; headache; heat sensation; heartburn; light-headedness; muscle cramps; nausea; nervousness; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); fainting; fever, chills, or persistent sore throat; mental or mood changes; red, swollen, blistered, or peeling skin; severe or persistent dizziness or light-headedness; shortness of breath; slow, fast, or irregular heartbeat; sudden, unusual weight gain; swelling of the arms or legs; symptoms of heart attack (eg, chest, jaw, or left arm pain; numbness in an arm or leg; sudden, severe headache or vomiting); tender, bleeding, or swollen gums; tremors; unusual bruising or bleeding; unusual tiredness or weakness; vision problems; wheezing; worsening chest pain (eg, longer, more often, more severe); yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Nifedipine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; loss of consciousness; rapid, slow, or irregular heartbeat; severe dizziness or light-headedness.


Proper storage of Nifedipine:

Store Nifedipine at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nifedipine out of the reach of children and away from pets.


General information:


  • If you have any questions about Nifedipine, please talk with your doctor, pharmacist, or other health care provider.

  • Nifedipine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nifedipine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nifedipine resources


  • Nifedipine Side Effects (in more detail)
  • Nifedipine Dosage
  • Nifedipine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Nifedipine Drug Interactions
  • Nifedipine Support Group
  • 20 Reviews for Nifedipine - Add your own review/rating


  • Nifedipine Professional Patient Advice (Wolters Kluwer)

  • Nifedipine Monograph (AHFS DI)

  • Adalat Consumer Overview

  • Adalat CC Prescribing Information (FDA)

  • Afeditab CR Prescribing Information (FDA)

  • Nifediac CC Prescribing Information (FDA)

  • Nifedical XL Prescribing Information (FDA)

  • Procardia Prescribing Information (FDA)

  • Procardia XL Prescribing Information (FDA)

  • nifedipine Advanced Consumer (Micromedex) - Includes Dosage Information



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